Nuts & bolts 2018-06-30T13:41:23+00:00

Learn more: Lectures, primers, and articles

Watch a lecture

  • Markus Covert
    Stanford University, US
  • Maria Lluch-Senar
    Center for Genomic Regulation, ES
  • Zaida Luthey-Schulten
    University of Illinois Urbana-Champaign, US
  • Jonathan Karr
    Icahn School of Medicine at Mount Sinai, US
  • Derek Macklin
    Stanford University, US
  • Koichi Takahashi
    RIKEN, JP

Read the primer

An introduction to whole-cell modeling 
Karr JR & Goldberg AP

Primer

Attend a course

2020 WC Workshop 
June, 2020
New York, US

2019 WC School
April, 2019
CRG, ES

2017 WC School
September 4-7, 2017
CRG, ES

2016 WC School
April 3-8, 2016
CRG, ES

2015 WC School
March 9-13, 2015
Univ of Rostock, DE

Read a perspective

Covert MW. Simulating a living cell. Sci Am 2014. 

Carrera J & Covert MW. Why Build Whole-Cell Models? Trend Cell Biol 2015.  

Karr JR et al. The principles of whole-cell modeling. Curr Opin Microbiol 2015. 

Goldberg AP et al. Emerging whole-cell modeling principles and methods. Curr Opin Biotech 2017. 

Macklin DN et al. The future of whole-cell modeling. Curr Opin Biotechnol 2014.  

Szigeti B et al. A blueprint for human whole-cell modeling. Curr Opin Syst Biol 2018. 

Goldberg AP et al. Toward scalable whole-cell modeling of human cells. ACM Conf Prin Adv Discrete Simul 2016. 

Waltemath D et al. Community standards and software for whole-cell modeling. IEEE Trans Biomed Eng 2016. 

Read a research article

Karr JR et al. A whole-cell computational model predicts phenotype from genotype. Cell 2012.  

Sanghvi JC et al. Accelerated discovery via a whole-cell model. Nat Meth 2013. 

Kazakiewicz D et al. Systems and structural modeling reposition antibiotics. Comput Biol Chem 2015. 

Purcell O et al. Towards a whole-cell modeling approach for synthetic biology. Chaos 2013.  

Karr JR et al. WholeCellKB: model organism databases for whole-cell models. Nucleic Acid Res 2013. 

Karr JR et al. Toward parameter identification for whole-cell models. PLoS Comput Biol 2015. 

Karr JR et al. WholeCellSimDB: a database for whole-cell model predictions. Database 2014.  

Lee R et al. WholeCellViz: data visualization for whole-cell models. BMC Bioinformatics 2013.